OBJECTIVE: Exploration; age-specific and gender-specific effects of fluoride level in drinking water and the incidence of osteosarcoma.
From: The Eye Pathologist; Contributor: Gordon K. Klintworth Osteosarcoma (osteogenic sarcoma) is a highly malignant tumor. It characteristically presents between the ages of 10 and 30 years and has a male predominance. The tumor is usually treated with wide tumor resection and adjunctant chemotherapy. Despite treatment the prognosis is poor and a fatal outcome is the rule.
CONCLUSIONS: The exploratory analysis found an association between fluoride exposure in drinking water during childhood and the incidence of osteosarcoma among males but not consistently among females. (However, osteosarcoma in all cases are predominantly found in males)
Contributer: The Eye Pathologist, Duke University
Conducted and published by: Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, and Clinical Research Program, Children’s Hospital, USA. elise_bassin@post.harvard.edu PMID: 16596294 [PubMed - indexed for MEDLINE]
Strong Statement? Sounds insane? Read your toothpaste label.
NOTE: The list below, detailing the documented adverse effects of fluoride continues to be updated. Updates are inserted at the top. (the term “updates” meaning, most recent additions and may or may not mean most recently discovered)
Low birth weight in newbornsas a result of low hemaglobin levels in expectant Mother’s drinking fluoridated water. (see associated video, “Dr. A.K. Susheela on fluoride poisoning of the soft tissues”)
Obesity as fluoride has been shown to effect lipase production in pancreadic function
Alzheimer’s Disease
Weakening of bones, leading to an increase in hip and wrist fracture. Read More…
Dr. A.K. Susheela On Fluoride Poisoning, Low Birth Weight, and Effects on The Soft Tissues
About This Clip:
An interview with Dr. A.K. Susheela on her work in India diagnosing and treating patients with fluoride poisoning of the soft tissues. With early diagnosis the early symptoms are easy to reverse. Western doctors are totally oblivious of this disease which may be impacting millions of people living in fluoridated countries with a plethora of common complaints. (by and in association with the “Fluoride Action Network”)
A not yet understood substance in water that 1, caused the presence of multiple teeth, pitting and cracking enamel, and white or brown spots. And, 2, showed decreased dental decay. This leads a group of dental professionals into years of yet unsolved answers. How is it that a chief chemist working for the Aluminum Company of America (ALCOA) is so interested as to discover and reveal the long unsolved mystery? The answer comes through asking the question.. “What reason would the Aluminum Company of America (ALCOA)have interest and of what benefit”?
The origins of the dental application of what we associate the use of FLUORIDE, begins with an individual at the dawn of his yet to be recognized career in orthodontic dentistry. It was 1901, yet to be doctor, “Fredrick McKay” was in Colorado Springs working as a dental associate for $75.00/ month. In this work McKay noticed patients with the presence of multiple teeth with white or brown spots (later termed “Colorado Brown Stain”) and in severe cases the enamel was pitted. He became disturbed that many of his fellow practitioners were apathetic about identifying the cause and solution to this cosmetic problem.
By 1905 Fredrick McKay had become interested in orthodontics and moved to St. Louis to begin his orthodontic training. While in St. Louis he noticed the brown stain was prevalent in that region, also. He continued his research in the area but was unable to find an answer.
In 1908 he returned to Colorado Springs due to health reasons and practiced orthodontics while continuing to investigate of the “Colorado Brown Stain“.
In May, 1908 he and other members of the El Paso County Odontological Society presented a patient at the Colorado Dental Association meeting to illustrate and promote interest in the condition. To his dismay little interest was manifested by those at the meeting.
In December, 1908a committee consisting of Drs. McKay, Fleming and Burton was formed by the El Paso County Odonological Society to examine the teeth of the public school children in the Colorado Springs area for evidence of the “Brown Stain”. On January 8, 1909 the School Board granted permission to examine the children and the dental society allocated $21.00 to cover the cost of the exams. During the spring of 1909 they examined 2945 children and were astounded to find that 87.5 percent were afflicted with some degree of stain or mottling, and those afflicted were native to the Pikes Peak region. There were many theories for the cause of the stain. Some felt it was limited to the poor; others felt it was due to eating too much pork or drinking milk from local cows; others attributed it to radium and still others thought it was due to a calcium deficiency in the local drinking water
Funding was minimal and Dr. McKay primarily used his own funds to support his research. In 1910 he was granted $300.00 from the City of Colorado Springs. The next year, while serving as president of the Colorado Dental Association, he received $150.00 to assist with his study. He applied for and received the first research grant for $800.00 from the National Dental Association to continue his research.
By 1915 it was agreed that something in the water was causing the brown stain. But test after test failed to identify the critical substance.
PHOTO caption: In 1908 Dr. McKay corresponded with Dr. G.V. Black, Dean of Northwestern University Dental School in Chicago about the unique Colorado Brown Stain. Dr. Black became interested and began to study the problem.
In 1909 Dr. Black came to Colorado Springs to see the stained enamel first hand. .By 1915 it was agreed that something in the water was causing the brown stain. This led to many years of research and study between the two men and culminated in the publication of their early report in Dental Cosmos in 1916 Testing through this period failed to identify the critical substance causing the Brown Stain.
photo: 1909: Dr. G.V. Black (Lt) visited Dr. F. McKay (Rt)
1916-1931: 15 years of continued research failed to yield an answer to exactly what it was in the Pikes Peak “Cryolite” unique region that was causing the “Brown Stain”
Excerpt from “Origins Part II: Fifteen year dental research mystery solved by Aluminum Industry: The first answer to mystery covering a total of 30 years came from research done by Dr. H. V. Churchill, chief chemist for the Aluminum Company of America (ALCOA). Dr. Churchill had read Dr. McKay’s report and ordered a specific test to identify trace elements. His studies revealed an unusually high percentage of fluoride in the water where mottled enamel and brown staining occurred. (hence the term.. “Dental Fluorisis”) The news about fluoride was exciting to McKay, though he did not know how the ALCOA chemist “got in touch with the situation”. When he asked Branting the latter did not explain that he kept the ALCOA people up-to-date about his correspondence with McKay and any developments, but replied: “I believe his attention was drawn to the situation by the publicity our town received in the newspapers through the release recently by ´Science Service´ of an item on the subject” read in “Part II, The Aluminum Connection
| © 2008